MARROW FAILURE

APLASTIC ANEMIA:

It is pancytopnia with hypocelluarity of the bone morrow means reduce of all blood count cell. It's very serious condition could leads to death.

CAUSES OF APLACTIC ANENIA:

Congenital – chemicals – drugs – radiation – infections.

Infiltration of bone marrow: like:

Acute leukemia – myeloma – lymphoma – carcinoma.

Abnormal bone marrow maturation:

Ex.

Myelodysplasia.

Megaloblastic anemia.

Excess destruction: as in hypersplenism.

Auto immune disease:

 witch cause antibody formation like in lupus erythematosus.

APLASTIC ANEMIA MANGEMENT:

The treatment course of aplastic anemia is very variable and ranged between different stages.  

Need to eliminate the  main cause of this kind of anemia.

Transfusion of red cells platelets.

Antibiotic therapy.

Bone marrow transplantation.

Immune suppressive therapy. 

Internal medicine.

Dr.Zafer Maklad

zafernm@yahoo.com